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Brain Symphony

What is Brain Symphony Music?

The benefits of listening to music in improving mood, attention, and stress reduction have been scientifically validated by numerous studies. We introduce special combinations of almost 'unnoticeable' sound effects to a person's chosen music. The listener typically doesn't notice the effects, but the brain 'perceives' them (this is easily measured by an electroencephalogram). The sound effects carry specially arranged multiple frequencies resonating with target brain oscillating networks. The goal of the special effects is to activate the whole brain to work more harmoniously and efficiently for a target task.

  1. Customizable
    • Personal choice of music + personal choice of brain symphony sound-filter premade for a target activity
    • Literally infinite number of choices to make 'personal' brain symphony music
    • Let customer 'create' his or her own brain symphony music
    • Accountable to individual 'variance or uniqueness' of brain.
  2. Personal choice of music will motivate to listen more often. The more one's brain experiences the brain entrainment, the more optimal the brain function becomes (neuroplasticity).
  3. Subtle ('weak'; 'unnoticeable') entrainment intensity renders more natural and effective entrainment than 'strong entrainment', and enables complete music appreciation due to 'unnoticeable' sound effects.
  4. Combinations of entrainment frequencies used in the brain symphony music mimic how our brain functions optimally and naturally.
  5. Incorporation of harmonics, nonlinear dynamics, deterministic chaos and biomimicry in the principles of the brain symphony making.
  6. Lets the user to engage in target or routine activities while listening; no need to set out extra-time for entrainment.

If you are interested in more science and medical research information.read more

Main Outcomes and Benefits

Listening to the brain symphony music enables you to use your whole brain and to become more effective, efficient and productive. By experiencing (listening) your choice of the brain symphony music repetitively, your brain becomes more balanced and efficient and healthier as the new patterns of activation and communication become ingrained in one's brain (habituated, learned; neuroplasticity). A more balanced and healthier brain reflects a more balanced and healthier person.

Applications

We all face such a challenging world, changing and evolving at an ever increasing pace. Such demands of the world take great toll on us physically and psychologically. The following are common problems all of us have regardless of cultures and ages:

  • "I can't concentrate!"
  • "I can't study or read more than 30 minutes!"
  • "I am very forgetful!"
  • "I am always tired and don't want to do anything!"
  • "My mood is always down!"
  • "I am stressed out and anxious all the time!"
  • "I can't fall asleep and I wake up frequently!"
  • "I wish to be more productive or happier!"

The brain symphony music can improve a variety of mental and physical conditions and the above are just some of its potential applications. We are constantly expanding its applications to relieve 'The Pain' we face living in this exciting but demanding world.

Science Behind

Brain Entrainment

Brain entrainment is a method to induce one's brain state to resonate or respond according to specially formulated external stimulations. The idea of brain entrainment has been in use throughout our history as well as our daily living. Listening to music, watching a movie, dancing, playing sports, meditation, reading, drinking coffee or alcohol, or enjoying a hobby, etc., are some examples that we use to change our brain state. Brain entrainment includes not only mental changes, but also physiological changes in the brain; evidenced in electroencephalogram or fMRI. In other words, there are physical changes in microscopic dimensions such as forming new communication connections among brain cells and effecting the release of neurotransmitters and neuropeptides and hormones. Therefore, brain entrainment has a great potential in improving the human condition if it is developed and used by responsible and competent hands.

Brain State/Activity

The human brain is a very complex system in its anatomical and functional interactions. A brain state in relaxation or learning, for example, is a resultant global brain function from activation of appropriately combined various 'core brain functions'. The core brain functions include arousal, attention, emotion, memory, cognition, and abstraction as well as sensory and motor systems. Each core brain function has its unique neuronal networks comprised of anatomical-functional connections of different parts of brain. For example, reading an article requires a proper degree of arousal, proper type of attention, proper type of emotion, activation of long and short term memory systems, activation of visual cortex and its association cortex, and proper activation of abstraction and rewarding system, etc. The degree of activation in each core brain function varies according to a task at hand.

Brain Waves

The anatomical and functional connections and communication among specific parts of the brain manifest as 'signature- oscillations' in the brain. Each brain network has its "natural" frequency or frequencies, and communicates with other networks mostly by "rhythmic oscillations". The brain waves captured by electroencephalogram (EEG) or electrocorticogram (ECG) show these rhythmic oscillations and can be divided by certain frequency ranges (rate of oscillation; cycles per sec): delta, theta, alpha, sensory-motor rhythm (SMR), beta, gamma, high gamma, etc. Each band has its unique sets of oscillator-networks generated by specific anatomical and functional connections among various brain structures. Each band also renders its unique brain function, and certain tasks such as reading or relaxation, etc. require balanced, harmonized activations and cooperation among the different brainwaves.

Brainwaves are typically broken up into ranges, each range being associated with different mental states. The five common brainwave ranges are listed below.

  • Delta: 0.5 to 4 Hz. The Delta level is normally associated with a deep dreamless sleep, trance state, and non-REM type of sleep.
  • Theta: 4 to 8 Hz. The Theta level is normally associated with recall, fantasy, imagery, creativity, inspiration, future planning, dreaming, switching thoughts, and drowsiness.
  • Alpha: 8 to 14 Hz. The Alpha level is associated with a non-drowsy but relaxed, tranquil state of consciousness, primarily with pleasant inward awareness; body/mind integration.
  • Beta: 14 to 30 Hz. The Beta level is associated with outward awareness, the taking in and evaluating of various forms of data received through the senses; it is present with worry, anger, fear, hunger, and surprise.
  • Gamma: 30 to 80 Hz. The Gamma level is not associated currently with any state of mind. Some effects have been observed, but currently not enough research has been done in this area to prove, or disprove, anything.

Science incorporated into making of Brain Symphony

Every brain symphony music uses the U.S. patented brain entrainment technology. The patented technology is based on forefront scientific knowledge; nonlinear dynamics, stochastic resonance, music effects on human, deterministic chaos, neuronal network model, neuronal oscillator, harmonics, biomimicry, cross frequency coupling of brain wave, frequency maxima of brain structures, neuropsychology, synchronization, EEG power spectrum, coherence, phase lag, Golden Ratio, hologram, brain waves, and entrainment. We are constantly updating our knowledge base to make the brain symphony better than today's best.

Brain Structures

The core brain functions are generated by activation of anatomical and functional brain connections among specific structures within the brain (brain stem, thalamus, limbic brain, cerebellum and hemispheres). (Pictures)

The Major Lobes of the Brain
Cross Section of the Brain
Outside View of the Brain

The brain is split into the left and right hemispheres by the longitudinal fissure. The different brain areas are segmented by deep grooves, called sucli, and by functional aspects. The largest part of the human brain is the cerebral cortex (cortex means bark in latin). This is an appropriate name, because the brain does its computation only on the six surface layers.
The very back part of the brain contains the cerebellum (little brain), which is attached to the Hindbrain. The Cerebellum is not very well understood, but it has been implicated in the coordination of movement. It is very old on an evolutionary scale, and you probably can't live without one.
Above the cerebellum lies the occipital lobe , which processes visual information.
Moving counter-clockwise, the next area is the parietal lobe , which processes many different sensory areas, and so might be an association area.
In front of the parietal lobe lies the Primary Sensory area. This area receives somatosensory input (touch sensations) from the entire body in a topographical mapping.
Right next to the Primary Sensory area is the Motor Area. If you were designing a brain you would want the Sensory areas right next to the Motor areas so that an organism could react very quickly to an incoming stimulus (like a baseball flying towards your head).
The Frontal Lobe handles the most complex thoughts. Damage to this area causes personality changes as well as other afflictions.

Limbic Lobe

This inside view of the brain shows the Limbic Lobe, which is not visible from outside the brain. The Limbic Lobe has been implicated in sexual and emotional behavior as well as the encoding of some memories.
The Basal Ganglia is a collection of nerve bundles that is primarily responsible for motor programming.
The Thalamus is a collection of pathways that connects peripheral sensory organs to the various sensory corticies. Behind the Thalamus is the Pineal Gland, which controls body rhythms and sexual activity.
The Hypothalamus controls the visceral nervous system, guiding actions such as thirst, temperature regulation, and glanduar secretions in the organs

Brainstem

This is a dissection of the very oldest portion of the brain, the part of the brain that sits on top of the spinal cord.
The Midbrain controls reflex patterns associated with vision and hearing.
The Pons serves as a relay station between the cerebral cortex and the cerebellum.
The Medulla controls vital functions such as respiration and heartbeat.
The Cerebellum controls sychronized movements.

Directions in the Brain

As we begin to talk about brain scans and locations of lesions, we need a common way of describing directions in the brain. The scanners that we use typically take slices, or planes, through the brain, and the major slices are given names.
The Median Plane cuts lengthwise through the middle of the brain.
The Saggital Plane is parallel to the Median Plane, but off the main axis.
The Coronal Plane is perpendicular to the Median Plane, running right between your ears.
The Horizontal Plane runs parallel to the ground as you stand upright.

Behavioral Neuroanatomy

Functions, Problems, Conditions and Treatment for Each Part of the Brain

  • PREFRONTAL CORTEX
    • Prefrontal Cortex (PFC) Functions
      • Focus
      • Forethought
      • Impulse Control
      • Organization
      • Planning
      • Judgment
      • Empathy
      • Emotional Control
      • Insight
      • Learning from mistakes
    • Prefrontal Cortex Problems
      • Short attn span
      • Impulsivity
      • Procrastination
      • Disorganization
      • Poor Judgment
      • Lack of empathy and insight
    • Some Conditions Affecting the PFC
      • ADHD
      • Depression, at rest
      • Brain Trauma
      • Dementia
      • Schizophrenia
      • Antisocial Personality Disorder
    • Prefrontal Cortex Treatments
      • Meds to increase dopamine
      • L-tyrosine
      • Biofeedback to increase PFC activity
      • Coaching/organizational help
      • Intense aerobic exercise
      • Relationship counseling
      • Stimulating activities
      • Higher protein diet
    • Prefrontal Cortex Meds
      • Stimulants
        • Adderall (mixture of amphetamine salts)
        • Dexedrine (destroamphetamine)
        • Ritalin/Concerta (methyphenidate)
        • Cylert (pemoline)
        • Desoxyn (methamphetamine)
  • ANTERIOR CINGULATE GYRUS
    • Anterior Cingulate (AC) Functions
      • Brain's gear shifter
      • Cognitive flexibility
      • Cooperation
      • Go from idea to idea
      • See options
      • Go with the flow
    • Anterior Cingulate Problems
      • Gets stuck
      • Worries
      • Holds grudges
      • Obsesses
      • Compulsions
      • Addictions
      • Oppositional
      • Argumentative
      • Inflexible
      • Trouble shifting attention
    • Some Conditions Affecting the AC
      • OCD
      • Anxiety disorders - get stuck
      • Addictions
      • Oppositional Defiant Disorder
      • Eating Disorders
      • Chronic pain
      • PTSD
      • PMS
    • Anterior Cingulate Treatments
      • Meds to increase serotonin
      • 5-HTP/St. John's Wort
      • Biofeedback to calm AC activity
      • Cognitive/behavioral strategies
      • Intense aerobic exercise
      • Relationship counseling, anger management
      • Lower protein/complex carbs diet
      • Anterior Cingulate Meds
      • SSRIs (Paxil, Zoloft, Celexa, Prozac, Luvox)
      • Effexor, use XR prep and start slowly
      • New, novel antipsychotic in refractory cases
      • St. John's Wort may help
  • TEMPORAL LOBES
    • Temporal Lobe (TL) Functions
      • Understand/use language
      • Auditory learning
      • Retrieval of words
      • Emotional stability
      • Facilitation long memory
      • Read faces
      • Read social cues
      • Decoding verbal intonation
      • Rhythm, music
      • Visual learning
    • Temporal Lobe Problems
      • Memory problems
      • Headaches
      • Abdominal pain
      • Anxiety
      • Illusions
      • Aggression
      • Spaciness/confusion
      • Religious preoccupation
      • Hypergraphia
      • Seizures
      • Learning problems
      • Dart thoughts
    • Some Conditions Affecting the TLs
      • Head injury
      • Dissociation
      • Anxiety
      • Temporal lobe epilepsy
      • Amnesia
      • Serious depression
      • Left side - aggression, dyslexia
      • Right side - autistic apectrum disorder
    • Temporal Lobe Treatments
      • Meds to increase GABA (anticonvulsants)
      • GABA
      • Biofeedback to stabilize TL function
      • Remembering positive experiences
      • Sleep
      • Music
      • Relationship counseling, anger management
      • Increased protein diet
    • Temporal Lobe Meds
      • Anticonvulsants, often with a stimulant
        • Neurontin (gabapentin)
        • Topamx (topiramate)
        • Depakote (divalproate)
        • Carbatrol/Tegretol (carbamazepine)
        • Lamictal (lamotrogine)
        • Gabatril (tiagabine)
        • Dilantin (phenytoin)
  • BASAL GANGLIA
    • Basal Ganglia Functions
      • Sets body's idle
      • Controls smooth movement
      • Sets anxiety levels
      • Modulates motivation
      • Mediates pleasure
    • Basal Ganglia Problems
      • Increased activity
        • Irritability
        • Anxiety, panic
        • Hypervigilance
        • Conflict avoidant
        • Tension
        • Predicts worst
        • Excess motivation
      • Decreased activity
        • ADD like symptoms Decreased motivation
    • Some Conditions Affecting the Basal Ganglia
      • Anxiety Disorder
      • Tourette's/tics
      • OCD
      • PTSD
      • Movement disorders
    • Basal Ganglia Treatments
      • Meds to calm basal ganglia
      • Valerian root
      • Body biofeedback
      • ANT therapy
      • Hypnosis, meditation
      • Relaxing music
      • Assertiveness training
      • Limit caffeine/alcohol
    • Basal Ganglia System Meds
      • Antianxiety Meds
        • Benzodiazepines
        • Buspar (buspirone)
        • Antidepressant Meds
        • Anticonvulsants
        • Propranolol
  • DEEP LIMBIC SYSTEM
    • Deep Limbic System (DLS) Functions
      • Charges memories
      • Modulates motivation
      • Sets emotional tome
      • Appetite and sleep cycles
      • Bonding
      • Sense of smell, libido
      • Body temp/flight or fight response
    • Deep Limbic System Problems
      • Negativity, guilt, blame
      • Anger, irritability
      • Inward directed sadness
      • Low motivation/energy
      • Sleep/appetite problems
      • Low self-esteem
      • Social isolation
      • Loss of libido
    • Some Conditions Affecting the DLS
      • Depression
      • Cyclic mood disorders
      • Pain syndromes
    • Deep Limbic Treatments
      • Meds to increase norepinephrine/dopamine/serotonin
      • DL phenylalanine, SAMe,L-tyrosine
      • Cognitive-behavioral strategies
      • Biofeedback, increase left prefrontal activity
      • Intense aerobic exercise
      • Relationship counseling
      • Increased protein diet - The Zone
    • Deep Limbic System Meds
      • Antidepressants
        • Willbutrin (buprion)
        • Effexor (venlafaxine)
        • Norpramin (desipramine)
        • Tofranil (imipramine)
        • SSRIs
        • MAOIs
  • PARIETAL LOBES
    • Parietal Lobes Functions
      • Anterior PL
        • Processes sensory information
        • Localize touch, pressure, pain, and temperature on the opposite side of the body side
      • Superior PL
        • Spatial processing
        • Visual guidance of hands, fingers, eyes, and limbs, head
        • Responsive to eye movements
        • Visual motor guidance for reaching and grabbing objects
        • Tactile recognition
        • Information on limb position
        • Localize objects around us
        • Directing movement in space
        • Detecting stimuli in space
        • Distinguishing left from right
        ** posterior parietal - prefrontal track connections
      • Inferior PL
        • Spatial cognition, such as reading and arithmetic (borrowing complex numbers)
        • Create visual maps
        • Read Maps
      • Anterior PL Problems
        • Impaired position sense
        • High sensory thresholds
        • Decreased light touch sense
        • Decreased 2 point touch
        • Decreased double simultaneous touch
        • Astereognosia (can't tell what things are by feeling them)
        • Anosagnosia (denial of illness)
        • Anosdiaphoria (indifference to illness)
        • Autotopagnosia (inability to localize or name body parts - usually on the left side)
        • Asymbolia for pain (absence of normal reaction to pain)
        • Asomatognosia (loss of knowledge or sense of one's own body - usually right side problem)
        • Posterior PL Problems
      • Superior
        • Balint Syndrome - cannot reach for objects (optic ataxia)
        • Trouble with spatial processing
        • Poor visual guidance of hands, fingers, eyes, and limbs, head (hard time catching a ball)
        • Poor tactile recognition
        • Poor knowing of limb position
        • Hard time directing movement in space (trouble flying a kite)
        • Hard time distinguishing left from right
      • Inferior PL
        • Dyslexia
        • Acalculia
      • Right PL Problems
        • Neglect of left side (such as in drawing a clock, left side of drawing a person, left side of words, shaving)
        • Unaware anything is wrong or a problem is present
        • Constructional apraxia (impaired at combining blocks to build a design or doing puzzles)
        • Impaired copying, paper cutting, spatial relations, drawing maps, dressing)
      • Left PL Problems
        • Finger agnosia (can't tell position of finger with eyes closed)
        • Agraphia (trouble writing)
        • R-L confusion
        • Gertsmann syndrome (first 3 items)
        • Acalculia
        • Dyslexia
        • Errors in grammar
        • Apraxia
        • Inability to copy movements or make gestures
  • CEREBELLUM
    • Cerebellum Functions
      • Motor control
      • Posture, gait
      • Executive function, connects to PFC
      • Speed of cognitive integration (like clock speed of computer)
    • Cerebellum Problems
      • Gait/Coordination problems
      • Slowed thinking
      • Slowed speech
      • Impulsivity
      • Poor conditioned learning

Evidence / References

  1. EEG/QEEG
    • EEG (electroencephalogram): records dynamics of electrical potential changes generated by brain activities. Each brain state has unique EEG shape and speed of interactions (frequencies). Unhealthy or disease related EEG also has unique features such as in dementia, stroke, some psychiatric disorders, or epilepsy.
      EEG is composed of combinations of various brain waves. Brain wave is most commonly characterized by its speed.
    • QEEG: Quantitative EEG (QEEG) is a way of mathematical analysis of EEG. By special computation according to mathematical formula, EEG data can provide quantified brain functions: measures of brain wave power and communication.
    • QEEG Parameters:
      • Absolute amplitude; measures power of brain activity in different parts of brain. The power of different brain waves, determined by its speed, is measured at different locations of head. Too much or too small power may indicate a problem achieving optimal brain functions.
      • Coherence; measures sharing of common brain wave generators, in other words, it assesses for connectivity between two different areas of brain. Too much or too little connectivity may indicate a problem achieving optimal brain functions. Too much connectivity may indicate parts of the brain stuck together losing freedom of communicating with other parts of the brain. Too little connectivity may indicate lack of communication between the parts of the brain lacking healthy cooperation between the parts.
      • Phase lag; measures the time taken to communicate from one part of the brain to another. Shorter time of communication may indicate faster processing of information and longer for slower processing speed. Too fast or too slow processing speed may indicate a problem achieving optimal brain functions. In optimal brain, frontal parts of brain have faster processing speed and posterior (back) parts with slower processing speed.
      • Amplitude asymmetry; measures ratio of power between two different areas of brain.
      • Correlations between EEG measures and intelligence have been reported in numerous studies. Increased EEG power in the alpha and the beta band has been positively related with high intelligence. The network measures of EEG (coherence, amplitude asymmetry and phase delay) typically report a positive correlation of intelligence to faster processing in frontal connections (shorter phase delay of frontal connections) and widespread neural complexity-differentiation (low coherence in the widespread brain, and high amplitude asymmetry and long phase delay in the parietal and occipital-brain). Lastly, optimal levels of arousal (high EEG power in the alpha and beta band and low EEG power in the delta band) may also play a significant role in high intelligence.
  2. Experimental Data

    The following sample EEG data were obtained from a healthy 28 year old subject after listening to brain entrainment music developed with the present invention. The music file used in the experiment included simultaneous playing of the following entrainment frequencies: primary target 13, secondary target 20, auxiliary 4-7.83-10, and binding 40. EEG was recorded before and after listening to the music with entrainment. The EEG was transformed into the time averaged power spectrum by the fast Fourier transformation (FFT), and the absolute power, the amplitude asymmetry, the coherence and the phase lag (delay) were calculated for the pre-music and the post-music EEG records. Then, differences between the pre-music and the post-music EEG measures were calculated and the summaries were tabulated below.

    FFT Absolute Power Difference (uV Sq)
    Delta Theta Alpha Beta
    1.0-4.0 Hz 4.0-8.0 Hz 8.0-12.0 Hz 12.0-25.0 Hz
    Frontal -2.06817 0.035514 0.507986 1.349327
    Parietal 0.238238 0.237919 0.988855 2.37972
    Occipital -0.25531 0.378248 4.098792 3.957911
    Temporal -0.26666 0.118243 1.00812 1.004623
    Midline -0.28923 0.288964 1.120391 2.121257
    AVG -0.52822 0.211778 1.544829 2.162567

    Table 1. EEG power changes in different frequency bands (postmusic power - premusic power)

    Positive values indicate increase of the EEG power after listening to the music and negative indicating decrease of the EEG power. There is significant increase of the alpha and beta band EEG power which has positive correlation to higher intelligence. Reduction of the delta EEG power as well as higher alpha and beta power may indicate improved arousal.

    FFT Amplitude Asymmetry Difference
    Delta Theta Alpha Beta
    1.0-4.0 Hz 4.0-8.0 Hz 8.0-12.0 Hz 12.0-25.0 Hz
    Frontal Pole -25.8515 -9.26157 -6.62464 -6.95288
    Frontal -4.52104 2.232517 -5.7564 0.212741
    Central 15.13005 2.409128 2.786828 7.301531
    Parietal 17.12817 3.930166 10.76838 9.17982
    Occipital -2.39672 3.141814 14.02479 -2.7017
    Temporal -5.17159 -5.92475 -11.325 -9.89949

    Table 2. The amplitude asymmetry changes in different frequency bands (post-music amplitude asymmetry - pre-music amplitude asymmetry)

    Positive values indicate lager amplitude asymmetry after listening to the music and negative indicating smaller amplitude asymmetry. There are predominant changes towards larger amplitude asymmetries in the parietal and occipital areas which has positive correlation to higher intelligence.

    Delta Theta Alpha Beta 1 Beta 2 Beta 3 High Beta
    1.0-4.0 Hz 4.0-8.0 Hz 8.0-12.0 Hz 12.0-15.0 Hz 15.0-18.0 Hz 18.0-25.0 Hz 25.0-30.0 Hz
    Frontal Pole 1.201566 1.73888 12.19602 2.064968 3.130233 -1.35306 -3.72074
    Frontal 0.600826 0.148135 9.320278 1.415749 1.163403 -1.53292 -1.13953
    Central 0.184601 -1.06582 6.678412 0.546687 -0.11074 -2.05146 0.112445
    Parietal -0.39807 -1.36489 6.37795 1.485628 -0.59629 -3.8468 1.229652
    Occipital 0.089541 -0.73833 5.69216 1.556764 -1.67304 -2.23053 2.441093
    Temporal 1.513216 0.715221 9.77164 3.616797 1.147255 -1.49731 -0.2353
    Midline 4.623566 -2.72942 4.985236 -2.96003 1.9035 -6.2998 -2.93906

    Table 3. The coherence changes in different frequency bands (postmusic coherence - premusic coherence)

    Positive values indicate higher coherence after listening to the music and negative indicating lower coherence. There are lower beta2 and beta3 coherences in the parietal and occipital areas which has positive correlation to higher intelligence. There are also higher coherences across the alpha and beta1 bands suggesting increased influence of the thalamocortical oscillations providing temporal window for synchronization of faster local activities.

    FFT Phase Lag Difference (Deg)
    Delta Theta Alpha Beta
    1.0-4.0 Hz 4.0-8.0 Hz 8.0-12.0 Hz 12.0-25.0 Hz
    Frontal Pole 9.039807 -10.0606 -13.5808 -6.62536
    Frontal 4.833648 -0.75654 -8.90163 -3.10543
    Central 2.108318 -1.22315 -4.30908 -1.47164
    Parietal -3.52584 -0.07179 0.981638 0.316739
    Occipital -11.6815 11.56418 9.645469 2.721287
    Temporal 3.10981 -3.78096 -4.91546 -0.41377

    Table 4. The phase lag changes in different frequency bands (post-music phase lag - pre-music phase lag)

    Positive values indicate longer phase lag after listening to the music and negative indicating shorter phase lag. There are predominant changes towards shorter alpha and beta phase lag in the frontal area and towards longer alpha and beta phase lag in the parietal and occipital areas which has strongest positive correlation to higher intelligence.

EEG Changes by Listening to a sample of the Brain Symphony Music:

Brain Symphony Scientific validation

Each line of tracing represents EEG recording on a scalp location, total of 17 recording locations on the scalp. For example, "F7-A1" represents left anterior temporal area and "F8-A2" for right anterior temporal area. "Wavy line" (ups and downs) reflects dynamical changes of electrical potential (in micro voltages) which is generated by brain activities along timeline (in seconds). Height of the wave represents amount of electrical potential ("power") generated by brain network responsible for the wave. Width of the wave reflects 'speed' of oscillation (vibration) of the wave, frequency (cycles per sec), so the narrower the width is, the higher the frequency is; the wider the width is, the lower the frequency is. There are well known frequency ranges in the human brain: Delta, Theta, Alpha, Beta, and Gamma. Each frequency range has its unique functions and sources in the brain.

If you look at the wave patterns, height and wave forms, you should see the significant difference among EEGs before, during, and after listening to brain symphony music samples. On raw EEG tracing, changes in Alpha frequencies is easiest to notice since Alpha waves have regular sinusoidal wave form, high amplitude, and higher tendency to synchronize. Changes in the frequencies other than Alpha range are better studied by quantitative EEG analysis of power spectrum and their connective measures.

Case1. 78 year old female with 'forgetfulness':

Music: All the Way (Celine Dion & Frank Sinatra), The Prayer (Andrea Bocelli & Celine Dion), Sogno (Dream) (Andrea Bocelli), Nel Cuore Lei (Andrea Bocelli & Eros Ramazzotti), You're Still You (Josh Groban).

Entrainment Frequencies embedded in the music: specially combined Eight entrainment frequencies from alpha, theta, beta, and gamma frequency bands were used.

Sample Music: All the Way (Celine Dion & Frank Sinatra)

Before

Figure 1-1. EEG before listening to the brain symphony music.
Figure 1-1. EEG before listening to the brain symphony music.This is typical EEG pattern for normal resting condition.

During

Figure 1-2. EEG during listening to the brain symphony music.
Figure 1-2. EEG during listening to the brain symphony music. There were 'bursts' of higher powered alpha waves, reflecting subject's brain responding to the embedded entrainment frequencies.

After

Figure 1-3. EEG obtained five minutes after listening to the brain symphony music.
Figure 1-3. EEG obtained five minutes after listening to the brain symphony music. As you see, there were obvious enhancements of the EEG power and Alpha waves, and Alpha synchronization. These findings are strong indications of increased whole brain activation and increased synchronization within whole brain.

Case2. 28 year old female, working as RN, with no medical problem:

Music: Sogno (Dream) (Andrea Bocelli), My Heart Will Go On (Celine Dion), The Prayer (Andrea Bocelli & Celine Dion), Nel Cuore Lei (Andrea Bocelli & Eros Ramazzotti).

Entrain Frequencies embedded in the music: one frequency from alpha band was used.

Sample Music: Nel Cuore Lei (Andrea Bocelli & Eros Ramazzotti)

Before

Figure 2-1. EEG before the brain symphony music.
Figure 2-1. EEG before the brain symphony music.Again, this is typical EEG pattern for resting condition. Of note, her EEG has lower amplitude than the first case and this is not uncommon since there is individual variability of EEG in the normal people.

During 1

Figure 2-2. EEG during the brain symphony music.
Figure 2-2. EEG during the brain symphony music.Bursts of Alpha waves were starting to show up, indicating response from the entrainment frequencies.

During 2

Figure 2-3. EEG during the brain symphony music.
Figure 2-3. EEG during the brain symphony music.Higher powered and more synchronized wave patterns were more pronounced as the subject listened longer to the brain symphony music sample.

After

Figure 2-4. EEG after the brain symphony music.
Figure 2-4. EEG after the brain symphony music.As you see again, there were obvious enhancements of the EEG power and Alpha waves, and Alpha synchronization, indicating increased whole brain activation and increased synchronization within whole brain.

IQ changes after listening to the brain symphony music:

We calculated estimate of this person's IQ scores by using Brain Performance Index program (appliedneuroscience.com). The scores obtained were statistical estimate of subject's IQ scores based on multivariable analysis of QEEG variables. Please refer to following peer reviewed article for details of the analysis: Thatcher RW, Northa D, Bivera C. EEG and intelligence: Relations between EEG coherence, EEG phase delay and power. Clinical Neurophysiology 116 (2005) 2129-2141.

Case3. 17 year old girl, high school senior:

Music: All the Way (Celine Dion & Frank Sinatra), The Prayer (Andrea Bocelli & Celine Dion), Sogno (Dream) (Andrea Bocelli), Nel Cuore Lei (Andrea Bocelli & Eros Ramazzotti), You're Still You (Josh Groban).

Entrainment Frequencies embedded in the music: specially combined Eight entrainment frequencies from alpha, theta, beta, and gamma frequency bands were used.

Sample Music: Sogno (Andrea Bocelli)

Before

Figure 3-1. EEG before the brain symphony music.
Figure 3-1. EEG before the brain symphony music.

After

Figure 3-2. EEG after the brain symphony music.
Figure 3-2. EEG after the brain symphony music.As you see again, there were obvious enhancements of the EEG power and Alpha waves, and Alpha synchronization, indicating increased whole brain activation and increased synchronization within whole brain.

IQ changes after listening to the brain symphony music:

Predicted Neuropsychological Scores
Full Scale I.Q
Score 3-1. IQ before the brain symphony (17 year old girl).
Predicted Cognitive Performance
Neuropsychological TestsScaled ScoreMin SSMax SSZ ScoreMin ZMax Z
Information11.806.2217.370.24-1.461.94
Mathematics11.025.2516.780.10-1.731.93
Vocabulary11.505.5517.44-0.001.731.72
Digit Span8.872.9014.84-040-2.321.53
Picture Completion11.255.9816.530.00-1.751.86
Block Design9.963.7915.13-0.26-2.051.53
Coding9.493.6515.33-0.28-2.111.56
Mazes3.29-2.949.51-2.53-4.46-0.59
Full IQ103.6477.03130.25-0.20-1.881.48
Verbal IQ103.1479.10137.180.14-1.581.86
Performance IQ93.6272.56124.63-0.53-2.251.19

Predicted Z-Score Achievement and Neuropsychological Measures with 95% Confidence Intervals
Graph 3-1. IQ before the brain symphony (17 year old girl).

Table 3-1. IQ before the brain symphony (17 year old girl).Predicted full, verbal, and performance IQ scores were 103.64, 108.14, and 98.62, respectively before listening.
Predicted Neuropsychological Scores
Full Scale I.Q
Score 3-2. IQ after the brain symphony music (17 year old girl).
Predicted Cognitive Performance
Neuropsychological TestsScaled ScoreMin SSMax SSZ ScoreMin ZMax Z
Information12.056.4817.630.32-1.382.02
Mathematics13.297.5219.050.82-1.012.65
Vocabulary11.775.8217.710.07-1.651.80
Digit Span9.863.8915.83-0.08-2.001.85
Picture Completion10.365.0915.63-0.25-2.051.56
Block Design11.545.3717.700.20-1.591.98
Coding9.143.3014.93-0.39-2.221.45
Mazes4.52-1.7110.75-2.14-4.08-0.21
Full IQ107.3080.69133.910.03-1.651.71
Verbal IQ113.7184.67142.750.47-1.252.19
Performance IQ99.7773.71125.83-0.45-2.171.27

Predicted Z-Score Achievement and Neuropsychological Measures with 95% Confidence Intervals
Graph 3-2. IQ after the brain symphony music (17 year old girl).

Table 3-2. IQ after the brain symphony music (17 year old girl).Predicted full, verbal, and performance IQ scores were 107.30 (+3.66), 113.71 (+5.57), and 99.77 (+1.15), respectively after listening to the brain symphony music sample.

Case4. 17 year old boy, high school senior:

Music: 05-To Where You Are (Josh Groban), 09-Nel Cuore Lei (Andrea Bocelli & Eros Ramazzotti), 03-You're Still You (Josh Groban).

Entrain Frequencies embedded in the music: specially combined Five entrainment frequencies from alpha, theta, beta, and gamma frequency bands were used.

Sample Music: You're Still You (Josh Groban)

Before

Figure 4-1. EEG before the brain symphony music.
Figure 4-1. EEG before the brain symphony music.

After

Figure 4-2. EEG after the brain symphony music.
Figure 4-2. EEG after the brain symphony music.As you see again, there were obvious enhancements of the EEG power and Alpha waves, and Alpha synchronization, indicating increased whole brain activation and increased synchronization within whole brain.

IQ changes after listening to the brain symphony music:

Predicted Neuropsychological Scores
Full Scale I.Q
Score 4-1. IQ before the brain symphony music (17 year old boy).
Predicted Cognitive Performance
Neuropsychological TestsScaled ScoreMin SSMax SSZ ScoreMin ZMax Z
Information13.608.0319.180.79-0.912.49
Mathematics13.647.8719.400.930.902.76
Vocabulary12.266.3118.200.22-1.511.95
Digit Span9.883.9115.85-0.07-2.001.85
Picture Completion12.657.3817.920.54-1.272.34
Block Design12.330.1018.500.43-1.302.21
Coding13.697.8519.531.04-0.792.88
Mazes7.341.1113.56-1.27-3.200.67
Full IQ117.9391.32144.540.70-0.982.38
Verbal IQ116.3587.31145.390.63-1.102.35
Performance IQ115.8789.81141.930.61-1.112.33

Predicted Z-Score Achievement and Neuropsychological Measures with 95% Confidence Intervals
Graph 4-1. IQ before the brain symphony music (17 year old boy).

Table 4-1. IQ before the brain symphony music (17 year old boy).Predicted full, verbal, and performance IQ scores were 117.93, 116.35, and 115.87, respectively before listening.
Predicted Neuropsychological Scores
Full Scale I.Q
Score 4-2. IQ after the brain symphony music (17 year old boy).
Predicted Cognitive Performance
Neuropsychological TestsScaled ScoreMin SSMax SSZ ScoreMin ZMax Z
Information15.079.4920.651.24-0.462.94
Mathematics15.309.5321.051.46-0.373.28
Vocabulary14.148.2020.090.77-0.962.49
Digit Span10.634.6616.600.17-1.752.10
Picture Completion13.017.7418.280.66-1.152.47
Block Design15.098.9321.261.23-0.563.02
Coding16.8210.9822.662.030.193.86
Mazes7.190.9713.42-1.31-3.250.63
Full IQ126.2699.65152.861.23-0.452.91
Verbal IQ121.6992.65150.730.94-0.782.67
Performance IQ126.14100.08152.201.29-0.433.01

Predicted Z-Score Achievement and Neuropsychological Measures with 95% Confidence Intervals
Graph 4-2. IQ after the brain symphony music (17 year old boy).

Table 4-2. IQ after the brain symphony music (17 year old boy).Predicted full, verbal, and performance IQ scores were 126.26 (+8.33), 121.69 (+5.34), and 126.14 (+10.27), respectively after listening to the brain symphony music sample.

IQ Study with My brain symphony music

IQ changes after listening to the brain symphony music:

We calculated estimate of this person's IQ scores by using Brain Performance Index program (appliedneuroscience.com). The scores obtained were statistical estimate of subject's IQ scores based on multivariable analysis of QEEG variables. Please refer to following peer reviewed article for details of the analysis: Thatcher RW, Northa D, Bivera C. EEG and intelligence: Relations between EEG coherence, EEG phase delay and power. Clinical Neurophysiology 116 (2005) 2129-2141.

Case1. 17 year old girl, high school senior:

Music: All the Way (Celine Dion & Frank Sinatra), The Prayer (Andrea Bocelli & Celine Dion), Sogno (Dream) (Andrea Bocelli), Nel Cuore Lei (Andrea Bocelli & Eros Ramazzotti), You're Still You (Josh Groban).

Entrain Frequencies embedded in the music: specially combined Eight entrainment frequencies from alpha, theta, beta, and gamma frequency bands were used.

Sample Music: Sogno (Andrea Bocelli)

Predicted Neuropsychological Scores
Full Scale I.Q
Predicted Cognitive Performance
Neuropsychological TestsScaled Score
Information11.80
Mathematics11.02
Vocabulary11.50
Digit Span8.87
Picture Completion11.25
Block Design9.96
Coding9.49
Mazes3.29
Full IQ103.64
Verbal IQ103.14
Performance IQ93.62
Neuropsychological TestsScaled Score
Information12.05
Mathematics13.29
Vocabulary11.77
Digit Span9.86
Picture Completion10.36
Block Design11.54
Coding9.14
Mazes4.52
Full IQ107.30
Verbal IQ113.71
Performance IQ99.77

Case2. 17 year old boy, high school senior:

Music: 05-To Where You Are (Josh Groban), 09-Nel Cuore Lei (Andrea Bocelli & Eros Ramazzotti), 03-You're Still You (Josh Groban).

Entrain Frequencies embedded in the music: specially combined Five entrainment frequencies from alpha, theta, beta, and gamma frequency bands were used.

Sample Music: You're Still You (Josh Groban)

Predicted Neuropsychological Scores
Full Scale I.Q
Predicted Cognitive Performance
Neuropsychological TestsScaled Score
Information13.60
Mathematics13.64
Vocabulary12.26
Digit Span9.88
Picture Completion12.65
Block Design12.33
Coding13.69
Mazes7.34
Full IQ117.93
Verbal IQ116.35
Performance IQ115.87
Neuropsychological TestsScaled Score
Information15.07
Mathematics15.30
Vocabulary14.14
Digit Span10.63
Picture Completion13.01
Block Design15.09
Coding16.82
Mazes7.19
Full IQ126.26
Verbal IQ121.69
Performance IQ126.14
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